Lower GI series

Overview of the Procedure

The Lower GI series (barium enema) is a diagnostic procedure that utilizes radiographic imaging combined with oral or enema-administered contrast agents to observe the structure and function of the large intestine. This examination is primarily used to assess anatomical abnormalities, lesion locations, and extents within the colon, commonly in patients suspected of having colonic fistulas, strictures, or tumors.

Using X-ray fluoroscopy or digital imaging systems, physicians can observe the flow and distribution of contrast agents within the colon, aiding in the diagnosis of inflammatory bowel disease, congenital anomalies, or post-traumatic structural changes. This non-invasive method is especially suitable for patients unable to undergo colonoscopy.

Types and Mechanisms of the Procedure

The Lower GI series is performed via two methods: "rectal enema" and "oral radiography." The rectal enema involves directly introducing barium contrast into the rectum, while the oral method requires the patient to ingest contrast liquid prior to the procedure. Under X-ray imaging, the contrast highlights the mucosal and lumen morphology of the intestines, assisting physicians in identifying strictures, tumors, or fistulas.

During the examination, patients are instructed to change positions to ensure even coating of the intestinal wall by the contrast agent, with radiologic imaging performed simultaneously. Some procedures may incorporate air insufflation techniques, using gas and contrast density differences to more precisely reveal subtle mucosal lesions.

Indications

This examination is mainly suitable for patients suspected of having the following symptoms:

  • Unexplained abdominal pain, rectal bleeding, or changes in bowel habits
  • Suspected colonic fistula, intussusception, or congenital anomalies
  • Assessment of inflammatory bowel disease lesions

In certain cases, when colonoscopy is limited by technical factors (such as severe bowel angulation) or the patient cannot undergo anesthesia due to comorbidities, the Lower GI series can serve as an alternative diagnostic tool.

Usage and Dosage

Preparation involves bowel cleansing, typically including laxatives and a clear liquid diet. The contrast dose is adjusted based on body weight; adults usually receive 200-300 c.c. of barium suspension via enema, while the oral method requires multiple doses starting 12 hours before the procedure.

The examination lasts approximately 30 to 60 minutes, during which patients are asked to assume different positions to ensure even distribution of the contrast agent. When combined with air insufflation, additional carbon dioxide or air may be injected to enhance imaging contrast.

Benefits and Advantages

This procedure offers several benefits:

  • No anesthesia required, suitable for patients with compromised cardiopulmonary function
  • Allows visualization of the entire colon, unaffected by bowel angulation
  • Images can be stored for subsequent analysis

Compared to colonoscopy, the Lower GI series can observe the entire colon in one examination and is safer for patients with strictures. Its low-dose radiation technology significantly reduces radiation exposure, making it suitable for repeated follow-up assessments.

Risks and Side Effects

Potential side effects include:

  • Allergic reactions to barium (such as rash, difficulty breathing)
  • Risk of bowel obstruction (especially in patients with strictures)
  • Short-term bloating or constipation

Serious risks include bowel perforation or chemical colitis caused by residual contrast, with an incidence below 0.1%. Patients with allergies should inform medical staff before the procedure.

Precautions and Contraindications

Contraindications include:

  • Acute bowel perforation or peritonitis
  • Severe bowel obstruction or volvulus
  • Allergy to barium or iodine-based contrast agents

Medications affecting bowel motility, such as laxatives or calcium channel blockers, should be discontinued 48 hours prior. Pregnant women should avoid the procedure due to radiation risks, and alternative options should be considered if necessary.

Interactions with Other Treatments

Interactions with colonoscopy include:

  • Lower GI series cannot perform tissue biopsies
  • Colonoscopy can immediately treat small lesions but cannot visualize the entire length of a tortuous bowel

If patients have a history of contrast allergy, allergy testing may be required beforehand, or low-dose CT colonography can be used as an alternative.

Effectiveness and Evidence

Studies show that this examination has a sensitivity of 85-90% for detecting colorectal tumors and a specificity of over 95% for fistula diagnosis. The American Society for Gastrointestinal Endoscopy recommends using the Lower GI series as a primary screening tool for high-risk patients unable to undergo colonoscopy.

A 2020 systematic review indicated that this technique's accuracy in evaluating inflammatory bowel disease correlates highly with colonoscopy, especially in assessing lesions of the rectum and sigmoid colon.

Alternatives

Main alternatives include:

  • Colonoscopy (allows biopsy and treatment)
  • Virtual colonoscopy (CT colonography)
  • MRI enterography

Colonoscopy provides more precise lesion localization and tissue diagnosis but is more invasive. Virtual colonoscopy is non-invasive but still requires bowel preparation and involves radiation exposure. The choice should be based on individual patient conditions.

 

Frequently Asked Questions

What special diet or bowel preparation is required before the examination?

For 1 to 2 days before the procedure, a low-fiber diet is recommended, avoiding vegetables, whole grains, and foods that may leave residues in the intestines. On the day of the exam, bowel cleansing is necessary, typically involving laxatives or enemas to ensure the bowel is clean, resulting in clearer X-ray images. Medical staff will adjust the specific plan based on individual health conditions.

How can discomfort such as bloating or abdominal pain during the procedure be alleviated?

Gas is injected during the procedure to expand the intestines, which may cause bloating or mild pain. Deep breathing, changing positions to facilitate X-ray imaging, or informing medical staff about discomfort can help. Adjustments in gas injection speed are also possible. Usually, discomfort subsides within a few hours after the procedure.

What dietary and activity precautions should be taken after the examination?

It is recommended to consume light, easily digestible foods for 24 hours post-procedure and avoid overeating to prevent bloating. Gentle walking can promote gas expulsion, but strenuous activity should be avoided. If persistent abdominal pain, vomiting, or blood in stool occurs, medical attention should be sought immediately.

What factors might affect the accuracy of the results?

Incomplete bowel cleansing, inability to maintain specific imaging positions, or excessive bowel sensitivity causing muscle contractions can affect image clarity. Not following dietary restrictions or bowel preparation instructions may lead to incomplete results, necessitating a repeat examination.

How long after the procedure can I expect to receive the report?

Typically, the report takes 3 to 5 working days, with detailed analysis by a radiologist. Emergency cases may be prioritized, but routine reports require time for image processing and professional interpretation. A preliminary assessment can often be provided on the day of the exam for obvious abnormalities.