Tadalafil is an oral medication used to treat male erectile dysfunction (ED) and pulmonary hypertension. Its primary mechanism of action is the inhibition of phosphodiesterase-5 (PDE5), which relaxes blood vessels and promotes blood flow, thereby improving erectile function or alleviating symptoms of pulmonary hypertension.
This medication has a relatively long half-life, with effects lasting up to 36 hours after a single dose, which is why it is often referred to as the "weekend dose". Clinically, it is not only used for sexual dysfunction but also as a long-term treatment option for pulmonary hypertension.
Brand names include Cialis (used for ED treatment) and Adcirca (used for pulmonary hypertension). The generic name is Tadalafil. Different brands may vary in dosage or formulation, and should be used according to a physician’s prescription.
It belongs to the class of phosphodiesterase-5 (PDE5) inhibitors, with vasodilatory properties. These drugs mainly act on smooth muscles, increasing cyclic GMP levels in specific tissues to relax blood vessels.
Main indications include:
Additionally, some countries also approve its use for benign prostatic hyperplasia, but this indication may not yet be approved in Taiwan. Usage should be clarified with a pharmacist or physician.
Mild side effects include:
Serious side effects requiring immediate medical attention:
If any of the above symptoms occur, discontinue the medication immediately and seek medical attention.
Contraindicated groups include:
Pregnancy and breastfeeding safety are classified as Category C. Use during late pregnancy may harm the fetus. Women of reproductive age should use contraception. During treatment, avoid excessive alcohol consumption as it may exacerbate hypotension side effects.
Contraindicated interactions:
Other precautions:
For ED: Starting dose is usually 5-10 mg taken 30 minutes before sexual activity, no more than once daily. For pulmonary hypertension: Starting dose is 40 mg once daily, with gradual adjustment under medical supervision.
Swallow the tablet whole; do not chew. Taking with high-fat meals may delay absorption but does not significantly affect total absorption. Follow the physician’s instructions strictly; do not adjust the dose on your own.
If a dose for ED is missed and it is not close to the next dose time, take it immediately. If it is near the next scheduled dose, skip the missed dose and resume the regular schedule. Do not double dose.
For pulmonary hypertension, if a dose is missed, take it as soon as remembered and adjust the next dose time accordingly to prevent symptom worsening.
Overdose may cause severe hypotension, visual disturbances, or prolonged erection. Seek immediate medical attention and inform healthcare providers of the drug name and dosage. Hospital observation or antidote administration may be necessary.
If symptoms of shock occur (such as dizziness, cold sweat, weak pulse), call emergency services immediately and seek urgent medical care.
Good, I need to help the user generate frequently asked questions about Tadalafil in Traditional Chinese, following their format requirements. First, I need to confirm that the correct translation of Tadalafil in Traditional Chinese is "他達拉菲爾," right? I should ensure this name is used throughout all questions and answers.
Next, since the user wants to avoid basic questions like “What is Tadalafil?”, I should focus on practical aspects such as medication methods, side effect management, drug interactions, lifestyle considerations, etc. I need to ensure each question is unique, not repetitive, and provides new information.
The first question could consider the timing of medication and the impact of diet, such as whether it needs to be taken on an empty stomach or with food. The second question could be about managing side effects like headache or facial flushing. The third could involve interactions with other heart disease medications, such as contraindications with nitrates. The fourth might concern dietary restrictions during medication, such as avoiding high-fat foods. The fifth could address the safety of long-term use and whether regular check-ups are necessary.
Make sure each question is wrapped in
with the correct tags, concise (3-4 sentences), and in Traditional Chinese. No English, except possibly the drug name, which should already be translated. Check for content repetition and ensure all formatting requirements are met, such as no numbered questions, only
tags, correct nesting, and professional yet understandable language suitable for patients and caregivers.
Verify pharmacological information, such as whether Tadalafil has contraindications with nitrates and recommendations for long-term use. Also, confirm if high-fat diets indeed delay absorption, and ensure all information is based on the latest medical data to avoid outdated or inaccurate content. Carefully organize these questions in a logical order, covering different aspects like usage method, side effects, drug interactions, diet, and long-term safety to meet diverse user needs. Check formatting for correctness, ensuring no extra structural tags and proper use of HTML tags.
服用他達拉菲爾時是否需要配合特定飲食？
建議在使用他達拉菲爾時避免高脂肪餐點，因高脂飲食可能延長藥物作用時間。一般建議空腹或進食後服用，但需避免與大量脂肪類食物同時攝取，以確保藥效穩定。若對用藥時間有疑慮，應諮詢醫師或藥師。
他達拉菲爾可能引起的臉部潮紅或頭痛如何緩解？
臉部潮紅和頭痛是常見副作用，通常為一過性反應。可透過降低初期劑量、避免酒精或熱源（如熱水澡）來減輕症狀。若症狀嚴重或持續，應立即停藥並連繫醫療人員評估是否需調整用藥計畫。
與其他心臟疾病藥物併用時需注意哪些交互作用？
他達拉菲爾與硝酸酯類心臟藥物（如硝酸甘油）有嚴重交互作用，可能導致血壓過度下降，禁止併用。使用心血管藥物前應告知醫師，包括降血壓藥或心臟病治療藥物，以避免風險。
藥效時間長達36小時，如何避免影響日常活動？
他達拉菲爾的長效特性可能增加偶發性勃起的風險。建議遵從醫師指示的固定劑量，避免自行增加頻率。若在非預期時間出現勃起持續超過4小時，需立即就醫，此為醫療急症。
長期使用是否會導致勃起功能依賴藥物？
目前無證據顯示他達拉菲爾會導致生理依賴性。此藥僅協助改善血流，不會削弱自然勃起能力。但需定期回診評估根本病因，並配合生活型態調整，以維持長期治療效果。
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