Venlafaxine is an antidepressant used to treat mood and psychological disorders, primarily by regulating neurotransmitters in the brain to improve symptoms. This medication belongs to the class of Serotonin and Norepinephrine Reuptake Inhibitors (SNRI), which increase the levels of serotonin, norepinephrine, and dopamine, and is suitable for severe depression, generalized anxiety disorder, and other conditions.
The therapeutic effects of venlafaxine usually become apparent after 2-4 weeks of continuous use. Patients must follow the physician's instructions to complete the full course and should not stop medication on their own. Its mechanism of action differs from other antidepressants and may be more effective for certain patient groups.
The generic name of this drug is Venlafaxine Hydrochloride. Common brand names include Effexor and various generic versions from different pharmaceutical companies. Available formulations include immediate-release capsules and extended-release capsules, with dosages adjusted according to the patient's age and severity of condition.
Venlafaxine is classified as a Serotonin and Norepinephrine Reuptake Inhibitor (SNRI). Unlike SSRIs, it has a stronger effect on norepinephrine. This class of medication can modulate multiple neurotransmitters and is suitable for patients who do not respond well to medications with a single mechanism of action.
Main indications include:
In certain cases, it may also be used for other mood disorders, but strictly under medical supervision and not for self-medication or expanded use beyond prescribed boundaries.
Mild side effects may include:
Serious side effects require immediate medical attention:
Contraindications: Those allergic to venlafaxine should not use this medication. Patients with severe liver or kidney impairment or narrow-angle glaucoma should use it cautiously. Use during pregnancy may increase fetal risks; women of childbearing age should discuss reproductive plans with their doctor.
Black Box Warning: This medication may increase suicidal thoughts, especially during initial treatment or dose adjustments. Patients should have regular follow-ups for mood assessment. If suicidal thoughts occur, notify healthcare providers immediately.
Contraindicated interactions include:
Interactions to watch for include:
The starting dose is usually 75 mg daily, divided into multiple doses. The doctor will gradually adjust the dose based on response, typically not exceeding 225 mg per day. Extended-release formulations should be swallowed whole without chewing, while immediate-release forms can be divided.
Take medication at the same time daily to maintain stable blood levels. If a dose is missed, decide whether to take it based on the time elapsed. Do not stop suddenly to avoid withdrawal symptoms such as dizziness or increased anxiety.
If a dose is missed and more than 4 hours remain before the next dose, take it as soon as possible. If close to the next dose time, skip the missed dose and resume the regular schedule. Never double the dose to compensate for a missed one, as this may increase side effects.
Overdose may cause severe symptoms:
If overdose is suspected, seek immediate medical attention. Gastric lavage or antidotes may be necessary. When seeking emergency care, bring the medication container and specify the dose taken for quick assessment.
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