The live attenuated influenza vaccine (LAIV) is a vaccine used to prevent influenza. It works by using weakened live viruses to stimulate the human immune system, thereby providing protection against the influenza virus.
This type of vaccine differs from traditional inactivated influenza vaccines, which use killed viruses. LAIV is noted for its ability to induce a more comprehensive immune response in the body.
LAIV belongs to the category of live attenuated vaccines. Its mechanism involves introducing weakened influenza virus strains to provoke an immune response in the body.
These attenuated viruses replicate mildly in the upper respiratory tract, stimulating the body to produce specific antibodies and memory cells. These immune components can provide protection when encountering wild-type influenza viruses in the future.
LAIV is mainly used for the prevention of seasonal influenza and is suitable for healthy individuals aged 2 to 49 years, especially children and adolescents.
This vaccine is particularly suitable for those who may have reactions to injectable influenza vaccines or prefer non-injectable options. However, it is not recommended for immunocompromised individuals or those with a history of severe allergies.
LAIV is usually administered via nasal spray, making it relatively convenient and non-invasive.
The standard dose is typically a single spray, containing an appropriate amount of attenuated virus strains. Healthcare providers will determine the specific dosing regimen based on the individual's health status and age.
The main advantages of LAIV include its ability to induce a more comprehensive and durable immune response, including cellular and humoral immunity.
Like most vaccines, LAIV may cause mild side effects such as nasal congestion, sneezing, cough, and slight fever.
However, these side effects are usually mild and resolve spontaneously within a short period.
LAIV is not suitable for everyone, especially certain populations requiring special attention.
LAIV may interact with other medications or treatments, especially those affecting the immune system.
For example, individuals on long-term corticosteroids or other immunosuppressants may need to avoid using this vaccine.
Studies show that LAIV is effective in preventing influenza, especially among children and adolescents.
Data indicate that this vaccine can effectively reduce the incidence of influenza and has a significant effect in preventing severe illness.
If LAIV is not suitable for certain individuals, traditional inactivated influenza vaccines or other forms of flu vaccines can be considered.
Doctors may recommend the most appropriate vaccine based on the individual's health condition and needs.
Before receiving the LAIV, it is recommended that patients ensure their health is stable and avoid fever or other serious health issues. Inform your doctor of any allergies or immune system-related diseases to ensure vaccine safety. Additionally, plan the vaccination appointment in advance and avoid vigorous exercise or exposure to extreme weather within 24 hours after vaccination.
What are the side effects of the live attenuated influenza vaccine?LAIV is generally safe, but mild side effects may occur, such as soreness, redness, or itching at the injection site. Some people may experience fatigue, headache, or mild fever, which usually resolve within a few days. If severe allergic reactions such as difficulty breathing or facial swelling occur, seek medical attention immediately.
What lifestyle precautions should I take after receiving the LAIV?After vaccination, maintain good lifestyle habits, including adequate sleep, a balanced diet, and moderate exercise to boost immunity. Avoid alcohol and smoking, as these behaviors may weaken immune function. Additionally, avoid contact with people with influenza or other infectious diseases for two weeks after vaccination to ensure optimal vaccine effectiveness.
How effective is the live attenuated influenza vaccine?LAIV can effectively reduce the incidence and severity of influenza, especially in healthy adults and children. Studies show that it provides approximately 70-90% protection before and after the flu season. However, the vaccine's effectiveness may vary depending on age, health status, and viral mutations, so preventive measures should still be observed even after vaccination.
How often should I receive the LAIV?It is generally recommended to receive the vaccine annually to cope with the different influenza strains each year. Children may need two doses at about four-week intervals during their first vaccination to ensure adequate immunity. Adults only need one dose each year to maintain protection. The vaccination frequency should be based on a doctor's advice to ensure optimal protection.
%201.svg)
Copyright © 2025 MedFrontiers. All Rights Reserved.
