Symptoms of Hepatitis

Hepatitis is a disease that affects liver function, and its symptoms can vary depending on the type of infection, stage of the disease, and individual constitution. Viral hepatitis (such as hepatitis A, B, and C) may present very differently from other types (such as alcohol-related or autoimmune hepatitis). Early symptoms are often mistaken for general fatigue or gastrointestinal discomfort, but if not diagnosed promptly, they can lead to long-term liver damage or even failure.

The severity of symptoms is directly related to the extent of liver damage, but it is noteworthy that some patients may be completely asymptomatic during the acute phase. Chronic hepatitis patients may experience long-term mild symptoms, which can gradually worsen or only be noticed when complications arise. Early recognition of symptoms and professional medical evaluation are key to preventing permanent liver damage.

Early Symptoms and Signs

Early symptoms of hepatitis are usually mild and non-specific, often mistaken for general fatigue or indigestion. Common early signs include persistent fatigue, muscle and joint aches, and mild upper abdominal discomfort. These symptoms may last for weeks, but patients may not immediately associate them with liver problems.

In the initial phase of acute viral hepatitis infection, some patients may experience flu-like symptoms such as fever, chills, and headache. These signs may appear within weeks after infection, but about 30-50% of hepatitis A patients show no obvious symptoms during the acute phase. Early symptoms of hepatitis B and C may be more subtle, but liver damage continues nonetheless.

Common Symptoms

When liver function is impaired beyond a certain point, characteristic symptoms become more prominent. Jaundice is the most distinctive manifestation, presenting as yellowing of the skin and sclera, darkening of urine to a tea color, and possibly grayish-white stool. These changes are direct evidence of the liver's inability to properly metabolize bilirubin.

  • Digestive System Abnormalities: including nausea, vomiting, sudden loss of appetite, and in severe cases, diarrhea or bloating.
  • Liver Area Tenderness: there may be tenderness in the right upper abdomen where the liver is located, especially noticeable during deep breathing or palpation.
  • Systemic Symptoms: unexplained weight loss, persistent low-grade fever, and characteristic signs such as palmar erythema (red palms).

In chronic hepatitis patients, long-term fatigue and concentration difficulties may be the main concerns. These symptoms are often mistaken for stress or sleep deprivation, leading to delayed diagnosis. Additionally, some patients may develop coagulation abnormalities, such as gum bleeding or increased skin bruising, related to impaired production of clotting factors by the liver.

Disease Progression and Symptom Changes

Differences Between Acute and Chronic Phases

Acute hepatitis symptoms may appear suddenly within weeks after infection, whereas chronic hepatitis often involves gradual symptom deterioration. During the acute phase, jaundice, severe vomiting, and abdominal pain can worsen rapidly within days, requiring immediate medical attention. Chronic hepatitis may remain asymptomatic for years before gradually developing symptoms related to cirrhosis, such as ascites and hepatic encephalopathy.

Warning Signs of Symptom Worsening

As liver damage progresses to cirrhosis, symptoms shift toward more severe systemic effects. Possible complications include:

  • Ascites: noticeable abdominal swelling accompanied by difficulty breathing
  • Hepatic Encephalopathy: confusion, disorientation, and seizures
  • Gastrointestinal Bleeding: rupture of esophageal varices causing vomiting blood or black stools

In hepatitis C patients, about 15-30% of acute infections progress to chronic stage, which may involve intermittent symptoms such as unexplained fever and joint pain, related to long-term immune response against the virus.

When to Seek Medical Attention

If any of the following symptoms occur, seek medical help immediately:

  • Severe fatigue lasting more than two weeks that affects daily activities
  • Jaundice (yellowing of skin or eyes)
  • Vomiting with inability to eat for more than 24 hours
  • Severe abdominal pain affecting breathing or movement

Even if symptoms seem mild, medical evaluation is advised if:

  • Recent high-risk behaviors (such as sharing needles or unsterilized piercing tools)
  • History of hepatitis exposure or family history
  • Unexplained weight loss (more than 5% of body weight per month)

Chronic hepatitis patients experiencing new symptoms (such as ankle edema or altered consciousness) on top of existing symptoms should consider these as warning signs of disease progression and seek prompt liver function assessment and treatment adjustment.

 

Frequently Asked Questions

What dietary principles should chronic hepatitis patients follow?

Chronic hepatitis patients should avoid high-fat, high-sugar, and processed foods to reduce liver metabolic burden. It is recommended to increase intake of high-fiber foods (such as whole grains and vegetables) and vitamin C-rich fruits, while controlling salt intake to prevent edema. Complete abstinence from alcohol is necessary, as alcohol exacerbates liver damage.

When should I seek medical attention after jaundice symptoms appear?

If jaundice (yellowing of skin or sclera) is accompanied by severe fatigue, tea-colored urine, or grayish-white stools, it indicates possible worsening liver function and requires immediate medical evaluation. Symptoms like ascites or altered consciousness are emergency indicators.

What are the differences in transmission routes between hepatitis B and hepatitis C?

Hepatitis B is mainly transmitted through blood, sexual contact, or vertical transmission from mother to child, whereas hepatitis C is primarily transmitted through blood contact, such as sharing needles or medical instruments. Both are not spread through casual contact (such as sharing meals), but personal blood and bodily fluid precautions are necessary.

What are common side effects of interferon treatment for hepatitis?

Interferon may cause flu-like symptoms (fever, chills), leukopenia, and mood swings. Some patients experience dizziness or fatigue. Regular blood tests are needed during treatment to monitor blood counts, and side effects should be communicated with the physician for dose adjustments.

Which vaccines can effectively prevent hepatitis virus infections?

The hepatitis A vaccine provides long-term immunity, and the hepatitis B vaccine requires three doses to produce sufficient antibodies. Currently, there is no vaccine for hepatitis C; prevention relies on avoiding blood contact and practicing safe behaviors.

Hepatitis