Upper GI series

Overview of Treatment

The Upper GI Series is a radiological diagnostic technique primarily used to assess structural and functional abnormalities of the esophagus, stomach, and duodenum. Patients are required to ingest a barium-based contrast agent, which makes the gastrointestinal tract visible on X-ray images, assisting physicians in observing swallowing, peristalsis, and morphological changes of the digestive tract lumen. This examination is commonly used for patients suspected of gastrointestinal obstructions, ulcers, strictures, or abnormal tumors, providing a non-invasive initial screening.

Types and Mechanisms of the Examination

This procedure is divided into "dynamic imaging" and "static imaging." Dynamic imaging tracks the movement of the contrast agent through the digestive tract, used to evaluate esophageal motility or gastric emptying speed; static imaging captures images at specific moments to show anatomical abnormalities such as strictures or foreign bodies. Mechanistically, the contrast agent creates a contrast under X-ray, making the mucosal surface, lumen shape, and movement patterns clearly visible.

Indications

Primarily applicable for the following symptoms or suspected conditions:

  • Difficulty swallowing or retrosternal pain, suspected of esophageal stricture or reflux esophagitis
  • Upper abdominal pain with gastrointestinal bleeding, suspected of gastric or duodenal ulcers
  • Gastrointestinal obstruction or foreign body retention
  • Congenital anomalies (such as pyloric stenosis) in pediatric patients

Method and Dosage

Patients should fast for 8-12 hours before the examination and follow physician instructions for bowel preparation. During the procedure, the patient drinks the contrast agent in front of the X-ray machine, and images are taken in different positions. The entire process lasts approximately 15-30 minutes. The amount of contrast agent is adjusted based on age and body weight; adults typically ingest 200-300 ml of liquid contrast medium.

Benefits and Advantages

The advantages of this examination include:

  • Non-invasive, no need for anesthesia or tissue sampling
  • Allows dynamic observation of gastrointestinal motility, such as esophageal peristalsis or gastric emptying
  • Lower cost compared to endoscopy, suitable for initial screening

Additionally, the imaging results can be provided immediately, helping physicians quickly interpret anatomical abnormalities such as fistulas or diverticula.

Risks and Side Effects

Common risks include:

  • The contrast agent may cause nausea or bloating, but most patients tolerate it well
  • Rare allergic reactions to the contrast agent, which may manifest as rash or difficulty breathing
  • Exposure to radiation, though the dose is lower than that of a typical CT scan

Serious risks: In patients with existing intestinal obstruction, ingesting contrast may worsen symptoms, so prior evaluation by a physician is necessary.

Precautions and Contraindications

Contraindications include:

  • Pregnant women (radiation may affect the fetus)
  • Severe intestinal obstruction
  • Allergy to iodine-based contrast agents

Patients should inform their doctor of any allergies or pregnancy potential before the examination and follow fasting instructions to ensure clear imaging.

Interactions with Other Treatments

If patients have recently taken potassium or bismuth-containing medications, it may affect image interpretation, so they should inform the physician in advance. This examination can be combined with endoscopy: for example, initially screening for abnormalities with the Upper GI Series, followed by gastroscopy for tissue biopsy. However, the interval between the two procedures should be at least 3-5 days to prevent residual contrast from interfering with subsequent examinations.

Effectiveness and Evidence

Studies show that the Upper GI Series has an 80-90% accuracy rate in diagnosing esophageal strictures or gastrointestinal ulcers, with particular advantages in evaluating dynamic peristaltic function. However, its sensitivity for mucosal lesions (such as gastritis) is lower, often requiring combination with endoscopy. Clinical guidelines recommend this examination as the first-line assessment for suspected structural abnormalities.

Alternatives

Other diagnostic methods include:

  • Gastroscopy: allows direct observation of the mucosa and tissue biopsy but is invasive
  • Computed Tomography (CT): provides higher resolution for perforation or tumor invasion
  • Ultrasound: suitable for some abdominal pain patients, but limited by gas or bony obstructions

The choice of alternatives depends on specific symptoms and medical resources; for example, for suspected esophageal foreign bodies, the Upper GI Series is preferred, while for suspected cancer, gastroscopy or CT may be directly arranged.

 

Frequently Asked Questions

Why is fasting for 8 to 12 hours necessary before the Upper GI Series?

Fasting before the procedure ensures the stomach and esophagus are empty, allowing clear visualization of mucosal structures on radiographs. Residual food in the stomach can interfere with the interpretation of abnormal lesions, so patients should follow medical instructions to fast and avoid water.

What should I do if I cough or feel throat discomfort while swallowing the barium?

If coughing occurs during the ingestion of the contrast agent, inform the technician immediately to pause the examination, rest briefly, and adjust the swallowing speed. Practicing small sips of warm water before the procedure can help adapt to the sensation of swallowing foreign material. Severe throat discomfort may lead the physician to consider alternative examinations.

Is it normal to experience bloating or diarrhea within a few hours after the examination?

Some patients may experience mild bloating due to swallowed air or residual contrast agent, which usually resolves within a few hours. If diarrhea persists for more than 24 hours or is accompanied by blood in stool, medical attention should be sought to rule out complications such as intestinal obstruction.

When can I resume normal diet and medication after the examination?

Generally, patients can eat clear liquids immediately after the procedure and gradually resume normal diet, avoiding high-fiber foods initially. For those on long-term gastrointestinal medications, medication can usually be resumed 1-2 hours after the examination as per physician instructions, along with increased water intake to promote contrast agent elimination.

Is the Upper GI Series safe for pregnant or breastfeeding women?

This examination involves radiation; pregnant women should avoid it. If pregnancy is discovered after the procedure, risk assessment with a physician is necessary. Breastfeeding women should stop breastfeeding for 24 hours and store breast milk in advance; once the contrast agent is fully cleared, breastfeeding can resume.