Colectomy

Overview of Treatment

Colon resection is a surgical procedure used to remove part or all of the colon (large intestine), primarily for treating severe colon diseases or cancer. This surgery can be performed as an open procedure or minimally invasive laparoscopic surgery, with the choice depending on the severity of the patient's condition and the location of the lesion.

The objectives include removing malignant tumors, excising necrotic tissue caused by inflammatory bowel disease, or managing emergencies such as intestinal obstruction. Postoperative management may involve creating a stoma or colostomy to temporarily or permanently divert fecal flow, determined by the extent of resection and the patient’s recovery status.

Types and Mechanisms of Treatment

Colon resection can be categorized into total colectomy (removal of the entire colon), subtotal colectomy (preserving the rectum), and segmental resection (local lesion removal). The primary mechanism involves excising diseased tissue to halt disease progression—for example, in colon cancer patients, removing the tumor and surrounding lymph nodes to reduce the risk of cancer spread.

Laparoscopic surgery involves inserting 3-4 small incisions for a camera and instruments, offering advantages such as smaller scars and quicker recovery; open surgery requires a larger incision and is suitable for complex lesions or emergency situations. Postoperative procedures may include bowel reconstruction, reconnecting healthy intestinal segments to restore gastrointestinal continuity.

Indications

Main indications include colon cancer, severe Crohn’s disease or ulcerative colitis, colon perforation, severe diverticulitis, and intestinal obstruction unresponsive to medication. Surgery is often necessary when medical therapy fails or the disease has advanced to stage III or IV cancer.

Other scenarios include prophylactic removal in familial adenomatous polyposis (FAP) or colon injury due to trauma. Physicians will evaluate the extent of the lesion, overall health status, and cancer staging to determine surgical suitability.

Usage and Dosage

The procedure is typically performed under general anesthesia, with duration depending on the extent of resection—total colectomy may take 4-6 hours. Laparoscopic surgery requires creating a pneumoperitoneum, while open surgery involves directly opening the abdomen. Patients usually stay in hospital for 5-10 days, with recovery taking approximately 6-8 weeks.

The concept of dosage does not apply here, but anesthesia doses and postoperative analgesics should be adjusted based on patient weight and age. Nutritional support doses (such as parenteral nutrition) may require personalized calculation.

Benefits and Advantages

Main benefits include:

  • Complete removal of malignant tumors or diseased tissue, reducing recurrence risk
  • Improvement of severe diarrhea and bleeding in inflammatory bowel disease patients
  • Prevention of emergency complications such as colon perforation or bleeding

The laparoscopic approach offers advantages like reduced tissue trauma, less postoperative pain, and shorter hospital stays; open surgery provides greater flexibility in managing extensive lesions. Long-term, surgery can significantly improve quality of life, especially in patients with severe inflammatory bowel disease.

Risks and Side Effects

Main risks include:

  • Intraoperative bleeding or vascular injury
  • Anastomotic leak (leakage at the surgical connection)
  • Deep vein thrombosis

Common side effects include short-term abdominal pain, paralytic ileus, and nutritional absorption issues; long-term complications may involve pelvic adhesions or electrolyte imbalances. Patients might need bowel training to adapt to a stoma.

Precautions and Contraindications

Contraindications include uncontrolled coagulation disorders, systemic infections, or severe cardiopulmonary failure. Preoperative assessment should include evaluation for comorbidities such as diabetes or cardiovascular diseases, with adjustments to blood sugar or blood pressure management as needed.

Postoperative monitoring for signs of infection, such as fever or abnormal drainage, is essential. Important warning: Immunocompromised patients should delay surgery unless there is an immediate life-threatening condition.

Interactions with Other Treatments

Pre- and post-surgical management may involve chemotherapy (e.g., neoadjuvant therapy for colon cancer) or biologic agents (e.g., anti-TNF drugs for inflammatory bowel disease). Antibiotic use should be coordinated to avoid conflicts with anticoagulants, reducing bleeding risk.

Radiation therapy may be used postoperatively for high-risk cancers, with an interval of at least 6 weeks to prevent tissue damage. A multidisciplinary team should jointly evaluate the treatment sequence.

Effectiveness and Evidence

Clinical studies show that colon cancer patients undergoing curative resection have a 5-year survival rate of 60-80%. Patients with inflammatory bowel disease who undergo total colectomy achieve symptom relief in over 80% of cases. The complication rate in experienced centers is controlled at 10-15%.

Laparoscopic and open surgeries show no significant difference in long-term survival, but minimally invasive procedures shorten recovery by about 40%. Large retrospective studies confirm that timely surgery reduces the risk of death from colon perforation by up to 70%.

Alternative Options

Alternatives include medical management (such as biologics for Crohn’s disease), endoscopic removal of ulcers or tumors, or radiation therapy to inhibit tumor growth. Early-stage colon cancer may be treated with local excision instead of full resection.

In patients with severe paralysis or cardiopulmonary impairment, temporary relief may be achieved through colostomy or ileostomy. When perforation or tissue necrosis occurs, surgery remains the definitive treatment.

 

Frequently Asked Questions

What specific dietary adjustments are necessary during the recovery period after colon resection?

The postoperative diet recovery generally occurs in three stages: initially, a clear liquid diet (such as rice water, apple juice) for 2-3 days; then gradually introduce low-fiber semi-solid foods (such as plain rice porridge, steamed fish), monitoring gastrointestinal response; finally, once the doctor confirms bowel function recovery, gradually resume normal diet. High-fiber, greasy, or gas-producing foods should be avoided for at least one month.

Is it normal to experience changes in bowel habits after surgery? How should this be managed?

Some patients may experience constipation or diarrhea due to changes in intestinal structure, which are common short-term adaptation phenomena. Doctors usually recommend increasing dietary fiber intake (such as chia seeds, oats) and regular exercise to promote bowel motility. If symptoms persist beyond two weeks or are accompanied by blood in stool, prompt medical review is advised to check for anastomotic stricture or other complications.

What long-term follow-up examinations are recommended after colon resection?

In the first year post-surgery, abdominal ultrasound or CT scans every 3-6 months are recommended to assess anastomotic healing. Thereafter, annual colonoscopy is advised to monitor residual bowel health. For inflammatory bowel disease, lifelong regular monitoring of inflammatory markers and tumor markers may be necessary.

What factors could cause unexplained weight loss during recovery?

Weight loss may be related to temporary impaired intestinal absorption, reduced activity levels post-surgery, or psychological factors affecting appetite. Doctors may recommend small, frequent meals, high-protein supplements, and personalized dietary plans from a nutritionist. If organic causes are excluded and weight loss persists, psychological support or hormonal therapy might be needed.

How long after colon resection can patients resume vigorous exercise or long-distance travel?

Generally, a recovery period of 6-8 weeks is needed before gradually resuming light activity once wounds are fully healed and no complications occur. Strenuous exercise should be delayed for 3-6 months until the intestinal sutures are fully strengthened. Before long-distance travel, ensure bowel habits are stable and carry medical documentation to handle potential postoperative emergencies.