Melanoma - Prevention

Melanoma is a highly lethal form of skin cancer, but its incidence can be significantly reduced through proactive prevention measures. Studies show that over 90% of melanoma cases are related to prolonged ultraviolet (UV) exposure. Therefore, prevention strategies should target environmental, behavioral, and genetic risks. Combining regular skin examinations with healthy habits can effectively lower the threat of malignant melanoma.

The key to melanoma prevention lies in a dual approach of "risk factor management" and "early detection." Daily protective measures include using physical sun protection, avoiding sun exposure, and establishing self-examination routines for the skin. Additionally, individuals with genetic predispositions should start systematic protection earlier and undergo regular professional screening by specialists.

Risk Factor Management

UV Protection

Ultraviolet (UV) radiation is the most critical environmental factor leading to melanoma. Daily protection should include:
1. Choosing broad-spectrum sunscreens with SPF 50+ and reapplying every two hours
2. Wearing long-sleeved clothing, wide-brimmed hats, and sunglasses during outdoor activities
3. Avoiding outdoor exposure during peak UV hours from 10 a.m. to 2 p.m.

  • Wearing UPF 50+ clothing can block 98% of UVA/UVB rays
  • Car windows and indoor glass do not block UVA; special attention should be paid to side windows

Genetic Risk Management

Family history is a significant prevention focus: if a first-degree relative (parent, sibling) has had melanoma, personal risk increases by 2-3 times. Genetic counseling is recommended, and full-body skin examinations should start as early as age 20, every six months. Genetic testing can evaluate mutations in related genes such as CDKN2A.

High-risk groups should establish a "daily skin self-examination" habit, paying particular attention to often overlooked areas such as palms, soles, and hairlines. The "ABCDE rule" is recommended for self-monitoring:

  • A (Asymmetry): Is the mole asymmetrical?
  • B (Border): Are the edges irregular or blurred?
  • C (Color): Is the color uneven or suddenly darkened?
  • D (Diameter): Is the diameter over 6 millimeters?
  • E (Evolution): Are the shape, size, or color continuously changing?

Lifestyle Adjustments

Modern lifestyles are clearly associated with melanoma risk. Research indicates that frequent exposure to artificial UV sources (such as tanning beds) increases risk by 75%. Adjusting the following behaviors can effectively reduce risk:

  • Completely avoid using tanning beds and UV tanning devices
  • Use "shade strategies" during outdoor activities, such as umbrellas or seeking shaded areas
  • Conduct preventive skin checks annually before summer

In urban environments, reflective surfaces like glass facades often lead to secondary UV exposure, which is frequently overlooked. When in high-reflection areas, in addition to applying sunscreen, it is advised to wear UPF clothing and use physical sunscreens containing zinc oxide.

Dietary Recommendations

Antioxidant Nutrient Intake

Consuming a diet rich in antioxidants can slow UV-induced DNA damage. Daily intake suggestions include:

  • Dark-colored fruits and vegetables (such as blueberries, spinach, purple cabbage)
  • Deep-sea fish rich in Omega-3 fatty acids (salmon, mackerel)
  • Vitamin D and folate supplements (following medical advice on dosage)

Excessive intake of animal fats and refined sugars may impair skin repair mechanisms. It is recommended to adjust the diet to include: 60% phytochemicals, 20% high-quality proteins, and 20% whole grains, while avoiding chemical additives in processed foods.

Dietary Precautions and Supplements

Some herbal supplements may enhance protective effects but should be used under medical supervision. The combination of vitamins C and E has been proven to boost skin cell repair capacity. Avoid excessive intake of photosensitizing supplements (such as St. John’s Wort), which can exacerbate UV damage.

Physical Activity Guidelines

Regular exercise can enhance immune surveillance against abnormal cells, but skin protection during activity is essential. Recommendations include:

  • Scheduling outdoor exercise in the early morning or evening
  • Using waterproof sunscreens and reapplying every hour
  • Wearing UPF 50+ sportswear

High-intensity interval training (HIIT) has been shown to increase natural killer cell activity. After exercise, it is important to wash the skin immediately and monitor for signs of sunburn. When swimming, use waterproof sunscreens and rinse immediately after getting out of the water, then reapply.

Regular Screening

Self-Examination Techniques

Perform a full-body skin self-exam monthly, using a full-length mirror and a handheld mirror to check hard-to-see areas. Examination steps include:

  1. Front and back of the torso, and the outer sides of limbs
  2. Between fingers, fingernails, and soles of the feet
  3. Hairline, behind ears, and private areas

Using a "skin map" recording method, take photos to document changes in moles’ shape and size. Warning signs include rapid expansion, ulceration that does not heal, or sudden darkening. Immediate medical consultation is advised.

Frequency of Professional Screening

People at average risk should have a professional skin check once a year, while high-risk groups (family history or history of sunburn) should be examined every six months. Doctors may use dermatoscopes or whole-body imaging systems for precise scanning. Early detection can increase treatment success rates by 95%.

Environmental or Workplace Considerations

Certain occupations (such as seaside workers or pilots) with high UV exposure should strengthen protective measures. Recommendations include:

  • Pilots should wear UV-protective goggles
  • Outdoor workers should reapply sunscreen every hour
  • Construction workers should use UV-protective shading equipment

Indoor workers should also note that glass does not block UVA. It is recommended to install UV-blocking films on office windows and wear UV-protective glasses while working at computers.

When to Consult Medical Professionals

Seek immediate medical attention if:

  • Existing moles change significantly in shape or color within 1-2 months
  • New skin growths appear with itching or bleeding
  • Family history and a mole with irregular "crow’s foot" borders are observed

Individuals over 40 or those at high risk should undergo genetic predisposition assessments annually. Doctors may recommend full-body imaging or liquid biopsy techniques. Any unexplained skin ulcerations lasting more than two weeks should be biopsied promptly.

Through integrating environmental protection, behavioral adjustments, and regular screening, the preventability of melanoma can reach over 70%. Establishing a personalized protection system and maintaining communication with healthcare teams are key strategies to reduce disease risk.

 

Frequently Asked Questions

How can I tell if a mole on my skin is at risk of melanoma?

Use the "ABCDE" principle for observation: A (Asymmetry): An abnormal mole may be asymmetrical; B (Border): Edges are irregular or blurred; C (Color): Uneven or darkening color; D (Diameter): Larger than 6 millimeters; E (Evolution): Changes in shape, size, or color over a short period. If multiple features are present, seek medical examination immediately.

Besides sun protection, what other ways can reduce melanoma risk in daily life?

Avoid sun exposure during peak UV hours (10 a.m. to 2 p.m.), and wear wide-brimmed hats, long-sleeved clothing, and UV-protective sunglasses. Regular self-examinations of the skin, especially on the back and legs, can help detect abnormalities early.

Are people with strong immune systems less likely to develop melanoma?

While immune function is related to melanoma development, it is not absolute. The immune system helps identify and eliminate abnormal cells, but prolonged UV exposure or genetic factors can still increase risk. Therefore, even healthy immune systems require strict sun protection and regular check-ups.

If there is a family history of melanoma, what specific precautions should be taken in daily protection?

Individuals with a family history should undergo professional skin examinations every 3-6 months, use SPF 30+ broad-spectrum sunscreens, reapply every two hours, and avoid UV lamps or tanning beds to reduce the risk of gene mutations.

Is sun protection necessary during winter or cloudy days to prevent melanoma?

Yes. UVA rays can penetrate clouds, causing DNA damage to the skin and increasing melanoma risk. Even in cold or cloudy weather, sunscreen should be applied when outdoors, and protective clothing should be worn. Snow reflection can also intensify UV exposure, so precautions should not be neglected.

Melanoma