Chronic fatigue management

Overview of Treatment

The management plan for Chronic Fatigue Syndrome (CFS) aims to improve patients' long-term fatigue, cognitive dysfunction, and physical discomfort. The treatment objectives are symptom relief, restoration of daily functioning, and prevention of symptom deterioration. Common treatment modalities include pharmacotherapy, Cognitive Behavioral Therapy (CBT), physical rehabilitation training, and nutritional adjustments.

Individualized treatment plans should be tailored based on the patient's age, severity of symptoms, and comorbid conditions. Most plans require 6-12 weeks to show effects, with regular assessments to evaluate efficacy and adjust strategies accordingly.

Types of Treatment and Mechanisms

Pharmacotherapy: Utilizes antidepressants (such as SSRIs) to regulate neurotransmitter levels or immune modulators to improve inflammatory responses. For example, low-dose amitriptyline can alleviate muscle soreness.

Cognitive Behavioral Therapy (CBT): Involves psychological counseling to modify patients' perceptions of fatigue and assist in establishing gradual activity plans. Therapists analyze patients' routines and set daily activity goals.

Indications

  • Chronic Fatigue Syndrome diagnosed according to CDC criteria
  • Unexplained long-term fatigue after ruling out other organic causes
  • Accompanied by autonomic dysfunction symptoms such as memory impairment or dizziness

Usage and Dosage

Pharmacotherapy should follow these principles:

  • Antidepressants: Starting dose typically 10-25mg daily, adjusted weekly
  • Physical therapy: Progressive exercise training 2-3 times a week, starting with 10-minute walks
  • Counseling: 60-minute sessions weekly, totaling 12-16 sessions per course

Benefits and Advantages

Multimodal treatment can improve quality of life in 60-70% of patients. Studies show:

  • CBT can reduce fatigue by 40%
  • Physical training can increase maximum oxygen consumption by 30%
  • Nutritional supplements (such as B vitamins) can improve energy metabolism in 30% of cases

Non-invasive therapies reduce the risk of side effects and are suitable for long-term management. Most patients can regain 70% of daily activity capacity within 6 months.

Risks and Side Effects

Potential side effects of medications include:

  • Antidepressants: Dry mouth, dizziness (about 15% of patients)
  • Overexertion: Muscle strains or symptom rebound
  • Counseling: Short-term mood fluctuations

Serious reactions: 0.5% of patients may experience drug allergies or abnormal blood glucose levels, requiring immediate discontinuation and medical attention.

Precautions and Contraindications

Contraindications include:

  • Patients with severe cardiac disease should avoid high-intensity physical training
  • Pregnant women should avoid SSRIs
  • Patients with severe suicidal tendencies should undergo psychological assessment first

Potential underlying causes such as hypothyroidism or sleep apnea should be excluded before treatment. During therapy, self-adjustment of medication dosage is prohibited.

Interactions with Other Treatments

When combined with analgesics, attention should be paid to:

  • NSAIDs may enhance hepatic metabolism of antidepressants
  • Herbal supplements (e.g., Ginkgo biloba extract) may reduce the effectiveness of anticoagulants

Patients undergoing chemotherapy should adjust exercise intensity and do so under oncologist supervision.

Effectiveness and Evidence

The 2020 Cochrane review indicates:

  • CBT can improve fatigue by 45%
  • Progressive exercise programs can restore work capacity in 60% of patients

Biofeedback therapy improved autonomic nervous system function in 68% of patients but has limited effects on severe cases.

Alternative Approaches

Non-traditional therapies include:

  • Traditional Chinese Medicine acupuncture: Regulates "Qi and blood flow" to improve fatigue
  • Meditation-Based Stress Reduction (MBSR): Lowers cortisol levels
  • Nutritional therapy: Supplements such as Coenzyme Q10 and Omega-3 fatty acids

Herbal treatments should be used cautiously, as some supplements (e.g., Astragalus) may affect immune function.

 

Frequently Asked Questions

What is the combined approach of Traditional Chinese Medicine and Western Medicine in treating chronic fatigue?

Traditional Chinese Medicine (TCM) treatments for chronic fatigue often include acupuncture, herbal medicine, and dietary therapy, working synergistically with Western medical approaches like nutritional supplementation or stress management. Physicians assess the patient's constitution and develop personalized plans, such as combining Western vitamins to regulate metabolism and immune function, strictly following medical instructions.

How to handle potential side effects when using Chinese herbal medicine?

Side effects of Chinese herbal treatments for chronic fatigue are usually mild, but some individuals may experience dry mouth or gastrointestinal discomfort. It is recommended to start with low doses and fixed administration times (e.g., after meals). If severe discomfort occurs, stop medication immediately and consult a physician. Do not adjust dosages independently.

What are specific recommendations for gentle exercise to alleviate chronic fatigue?

Gentle exercises such as walking, Tai Chi, or yoga are advised, lasting 20-30 minutes per session, 3-4 times a week, avoiding strenuous activities. Post-exercise, deep breathing or meditation can promote blood circulation. Exercise intensity should be comfortable enough not to cause shortness of breath and should be adjusted based on daily physical capacity.

What dietary precautions should be observed during treatment?

Avoid cold, greasy, and processed foods, such as cold drinks, fried foods, and products with preservatives, as they may worsen spleen deficiency symptoms. It is recommended to eat small, frequent meals, increase intake of dark vegetables and whole grains, and use medicinal ingredients like Astragalus and Angelica under medical guidance. Avoid self-medicating.

How should follow-up and relapse prevention be planned after treatment?

Periodic assessments of physical condition and symptoms should be conducted every 3-6 months, with a "Fatigue Diary" to record daily energy fluctuations. To prevent relapse, maintain regular routines, avoid staying up late, and undergo regular pulse and tongue diagnosis by TCM practitioners. Adjust herbal prescriptions or increase acupuncture sessions as needed.