Flecainide

Drug Overview

Flecainide is an antiarrhythmic medication used to treat cardiac arrhythmias. It is primarily used to control abnormal heart rhythms such as atrial fibrillation, atrial flutter, or supraventricular tachycardia.

This medication works by blocking sodium channels in cardiac cells, slowing the conduction of electrical impulses, thereby restoring normal heart rhythm. It is usually prescribed for patients who do not respond well to other treatments or cannot tolerate them.

Brand Names and Generic Name

The generic name is Flecainide. Common brand names include “Flecanide®” and others. Different countries may have different brand names, but in Taiwan and Hong Kong, the generic name “Flecainide” is commonly used directly.

Drug Classification

It belongs to the class of “Sodium Channel Blockers” and is categorized as a Class III antiarrhythmic drug. This classification mainly targets the electrophysiological properties of the heart.

Indications

Primarily used to treat the following conditions:

Note that this medication is only for severe cases where other treatments have failed, and should be used under strict evaluation by a cardiologist.

Common Side Effects

Mild side effects include:

Serious side effects require immediate medical attention:

Warnings and Precautions

Contraindications: Patients with heart failure, severe conduction block, or sick sinus syndrome should not use this medication. Women who are pregnant or breastfeeding must consult their doctor before use.

This drug carries a black box warning for the potential to induce fatal arrhythmias. Regular ECG monitoring is necessary during treatment, and strict adherence to medical instructions is essential.

Drug Interactions

Concurrent use with the following medications may increase risks:

When combined with beta-blockers or calcium channel blockers, dose adjustments are necessary to prevent electrophysiological abnormalities.

Dosage and Administration

The starting dose is usually 50-100 mg per day, taken once or twice daily. The specific dose should be adjusted based on age, liver and kidney function, and severity of symptoms.

The medication should be swallowed whole with water, not chewed or broken. Take at the same time each day to maintain stable blood levels. Alcohol should be avoided during treatment to prevent exacerbating side effects.

Missed Dose Management

If a dose is missed and more than 4 hours have passed, take it as soon as possible. If it is close to the next dose, skip the missed dose and resume the regular schedule. Do not double doses to make up for missed ones.

Do not increase the dose on your own due to missed doses; contact your doctor for dose adjustment.

Overdose Management

An overdose can cause severe arrhythmias or shock, requiring immediate medical attention. Symptoms may include extremely slow pulse, difficulty breathing, or loss of consciousness.

Emergency treatment involves ECG monitoring and intravenous administration of antiarrhythmic drugs; do not attempt to treat overdose yourself.

 


Frequently Asked Questions (FAQs):

氟卡尼的服用方式是什麼?是否需要空腹服用?

氟卡尼應按照醫師指示定時服用,通常建議空腹服用以確保吸收效果。服用時用一杯水整片吞服,避免咀嚼或掰開藥片。如忘記服藥,應立即補服,若接近下一次服藥時間則跳過,避免雙倍劑量。

如果在服用氟卡尼期間出現心跳不規則或頭暈,應該怎麼辦?

若出現心跳異常、頭暈或暈眩等症狀,應立即停止用藥並聯繫醫師。這些可能是藥物引起的心律不整或電解質失衡的跡象。醫師可能會調整劑量或安排心電圖監測,嚴重情況需緊急就醫。

與其他藥物合併使用氟卡尼時,有哪些風險需要注意?

氟卡尼可能與其他抗心律失常藥、抗生素(如大環內酯類)、抗真菌藥或β阻滯劑產生交互作用,增加心律不整的風險。用藥前應告知醫師所有正在使用的藥物,包括處方藥和非處方藥,以避免藥效增強或不良反應。

長期使用氟卡尼需要做哪些監測?

長期使用氟卡尼的患者需定期進行心電圖(ECG)和血藥濃度監測,以評估心律情況和藥物濃度是否在安全範圍內。醫師可能會安排血液檢查,監測肝腎功能及電解質,確保治療安全。

服用氟卡尼期間,日常飲食或運動有什麼注意事項?

避免攝取高鈣或高鈣拮抗劑的飲食,以防止電解質失衡加重心律異常。運動時建議選擇中低強度,若出現胸痛或心悸應立即停止並就醫。避免飲酒和刺激性食物,以降低副作用風險。

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