Stroke Treatment

Stroke treatment requires a personalized approach based on the severity of the patient's condition, the time of onset, and the type of lesion. The goal of treatment is to immediately restore cerebral blood flow, reduce brain cell damage, and prevent subsequent complications. Modern medicine combines various strategies including medication, surgery, rehabilitation, and lifestyle management to improve the chances of recovery.

Acute phase treatment is particularly critical. Acting within the "golden treatment window" of a few hours after onset can significantly improve prognosis. Treatment strategies should be differentiated based on the type of stroke (ischemic or hemorrhagic) and combined with long-term preventive measures to reduce the risk of recurrence. Rehabilitation and psychological support are also essential components of the recovery process.

Current Treatment Options

Current stroke treatment can be divided into three main stages: emergency care in the acute phase, rehabilitation in the subacute phase, and long-term management. The primary goal of acute treatment is to "recanalize occluded vessels" or "stop bleeding." For example, ischemic stroke patients may receive thrombolytic therapy, while hemorrhagic stroke patients may require surgery to remove hematomas or repair blood vessel abnormalities.

Subacute treatment focuses on functional recovery, including physical therapy, speech therapy, and occupational therapy to help patients regain daily activities. Long-term management emphasizes controlling risk factors such as hypertension and diabetes, combining medication and lifestyle modifications to reduce the risk of secondary stroke.

Medication Therapy

Acute Phase Medications

If ischemic stroke patients seek medical attention within 4.5 hours of onset, they may be eligible for tissue plasminogen activator (tPA) therapy. This medication dissolves blood clots but requires strict assessment of bleeding risk. Antiplatelet drugs like aspirin or prasugrel are used to inhibit platelet aggregation, typically administered outside the first 24 hours after onset.

  • Thrombolytic agents (tPA): Must be used within the golden time window to reduce disability by about 30%.
  • Anticoagulants: Such as warfarin or novel oral anticoagulants (NOACs), used in patients with atrial fibrillation to prevent cardioembolic events.
  • Antihypertensive drugs: Control of high blood pressure can reduce the risk of secondary hemorrhage, but excessive lowering should be avoided to prevent impairing cerebral perfusion.

Chronic Phase Medications

Long-term use of lipid-lowering drugs such as statins can stabilize atherosclerotic plaques and reduce arterial occlusion risk. Diabetic patients should also use insulin or oral hypoglycemic agents to maintain stable blood glucose levels and prevent vascular damage deterioration.

Non-Pharmacological Therapies

Surgical Treatment

Endovascular therapy is an invasive option for ischemic stroke, including mechanical thrombectomy or stent placement. This approach is suitable for large vessel occlusions unresponsive to medication, allowing direct removal of the clot via catheter. Hemorrhagic stroke may require craniotomy to evacuate hematomas or aneurysm clipping to prevent rebleeding.

Rehabilitation Therapy

Physical therapists design customized exercise programs to help restore muscle strength and balance. Speech therapists develop training for aphasia patients, using speech exercises and alternative communication tools to gradually recover communication abilities. Occupational therapy teaches patients to use assistive devices such as canes or walkers to enhance independence in daily life.

Lifestyle Management

Lifestyle modifications are key strategies for preventing secondary strokes. Dietary recommendations include adopting the DASH diet, reducing salt and fat intake, and increasing whole grains and vegetables. Regular monitoring of blood pressure, blood glucose, and lipid levels is crucial for delaying vascular disease progression.

  • Smoking cessation: Nicotine constricts blood vessels and accelerates atherosclerosis. Quitting smoking can reduce recurrence risk by up to 50%.
  • Regular exercise: 150 minutes of moderate-intensity exercise per week, such as brisk walking or swimming, can improve cardiovascular health.
  • Alcohol restriction: Men should limit alcohol intake to no more than 2 units per day, women to 1 unit, to prevent blood pressure fluctuations.

Future Treatment Directions

Gene therapy and stem cell therapy are current research hotspots. Stem cell transplantation aims to repair damaged brain tissue, while gene editing may correct genetic defects leading to atherosclerosis. Additionally, AI-assisted diagnostic systems can interpret imaging more accurately, aiding rapid decision-making by physicians.

Clinical trials for new antiplatelet and anticoagulant drugs are ongoing, such as dosage adjustments for direct oral anticoagulants (DOACs). Neuroprotective agents, although still in development, are viewed as potential breakthroughs by inhibiting apoptosis pathways.

When to Consult a Specialist

If symptoms such as unilateral limb weakness, speech difficulties, or visual disturbances occur, immediate medical attention is necessary. Even if symptoms temporarily resolve, a comprehensive evaluation by a neurologist is recommended. Patients with confirmed stroke should be followed up every 3-6 months to assess medication response and vascular status.

Seek emergency care immediately if any of the following occur:
1. Generalized seizures or altered consciousness
2. Sudden severe increase in blood pressure over 180/120 mmHg
3. Sudden memory decline accompanied by disorientation

 

Frequently Asked Questions

Why do acute stroke patients need treatment within the "golden three hours"?

The golden time for stroke treatment mainly applies to ischemic stroke. Patients receiving thrombolytic therapy (such as tPA) within 3 hours of symptom onset can significantly improve the chances of recanalization and reduce the risk of permanent neurological damage. Delays in treatment may lead to irreversible brain cell injury due to prolonged ischemia.

What are the differences in treatment strategies for different types of stroke?

Ischemic stroke is typically treated with clot dissolution or removal, while hemorrhagic stroke requires intracranial pressure control, hemostasis, or surgical evacuation of hematomas. Treatment varies depending on the cause; for example, antiplatelet drugs are suitable for atherosclerotic strokes, while cardioembolic strokes may require concurrent cardiac treatment. A multidisciplinary team evaluates and develops personalized plans.

When is the most effective time to start rehabilitation after a stroke?

Rehabilitation should begin as soon as the condition stabilizes, usually during hospitalization, with interventions including physical, occupational, and speech therapy. Early intervention promotes neuroplasticity and recovery of activity and independence, but the exact timing depends on the extent of neurological damage and overall health status.

Do stroke patients need to continue medication after discharge? What are common medications?

Yes, patients should continue prescribed medications such as antiplatelet agents (e.g., aspirin), lipid-lowering drugs (e.g., statins), or antihypertensives to reduce recurrence risk. Physicians may adjust the medication regimen based on complications. Regular follow-up is essential for monitoring physiological indicators; patients should not stop medication on their own.

How effective is acupuncture and traditional Chinese medicine in treating post-stroke sequelae?

Current evidence suggests that acupuncture can serve as an adjunct therapy in stroke rehabilitation, potentially improving limb weakness or numbness symptoms. It should be combined with Western medical treatment and not replace emergency interventions during the acute phase. Professional TCM practitioners and rehabilitation teams should perform it to ensure safety and efficacy.

Stroke