Asthma Treatment

The goal of asthma treatment is to control symptoms, prevent acute attacks, restore normal daily functioning, and reduce the risk of long-term complications. Treatment strategies typically combine medication use, environmental modifications, and patient self-management to establish personalized treatment plans. Modern medicine has developed various treatment options tailored to the severity of the condition and triggering factors.

Effective management requires regular follow-up and assessment of the disease. Physicians adjust treatment plans based on patient age, symptom frequency, and lung function test results. The key is long-term control and immediate management of acute episodes, along with educating patients on proper inhaler use and risk factor identification to enhance treatment efficacy.

Current Treatment Options

Asthma treatment is divided into "controller therapy" and "reliever therapy." Controller medications need to be used daily to reduce airway inflammation, while reliever medications are used for rapid symptom relief during acute attacks. Treatment plans are often adjusted stepwise, increasing medication intensity during worsening, and gradually de-escalating once control is achieved.

Controller Medications

Long-term control medications include inhaled corticosteroids (such as budesonide), leukotriene receptor antagonists (such as montelukast), etc. These drugs require daily use to suppress airway inflammation and allergic responses, reducing attack frequency. New biologic agents like anti-IgE monoclonal antibodies target specific allergic pathways and are suitable for severe asthma patients.

Acute Attack Medications

Short-acting bronchodilators (such as salbutamol) are the first choice for acute episodes, providing immediate relief from chest tightness and breathing difficulty. In severe cases, short-term oral corticosteroids (such as prednisone) or hospitalization may be necessary. All patients should carry rescue inhalers and know the correct usage procedures.

Pharmacological Treatments

Medication selection depends on patient age, symptom type, and comorbidities. Inhaled medications act directly on the airways with fewer side effects, but proper inhaler technique is essential. Physicians may combine different drug classes for optimal effect.

Inhaled Corticosteroids (ICS)

This class of drugs is the first-line long-term control, capable of suppressing chronic airway inflammation. Common forms include budesonide and fluticasone, which usually require several weeks of continuous use for maximum benefit. Some patients may worry about steroid side effects and misuse them; however, inhaled doses are low, with localized effects, and long-term safety has been confirmed.

Long-Acting Beta-Agonists (LABA)

LABA such as formoterol relaxes airway smooth muscle, with effects lasting over 12 hours. These are typically combined with ICS to form fixed-dose inhalers (e.g., salmeterol/fluticasone), avoiding monotherapy to reduce risks. Close monitoring is necessary to prevent drug resistance.

Non-Pharmacological Therapies

Non-drug interventions can enhance treatment outcomes, such as environmental control to reduce allergen exposure and behavioral therapy to help patients manage stress. Innovative techniques like breathing training and digital health tools are increasingly integrated into comprehensive care.

Allergen Immunotherapy

For allergic asthma, subcutaneous immunotherapy (SCIT) or sublingual therapy can gradually reduce allergic responses. Treatment usually lasts 3-5 years and is suitable for patients with positive tests for dust mites, pollen, and other specific allergens, under professional medical supervision.

Surgical and Emerging Therapies

Severe asthma patients may undergo bronchial thermoplasty, which uses radiofrequency energy to reduce airway hyperreactivity. Research into gene therapy and stem cell treatments aims to fundamentally repair airway structural abnormalities, but these are not yet widely available.

Lifestyle Management

Daily lifestyle adjustments are crucial for successful management. Avoiding tobacco smoke, controlling indoor humidity to prevent mold growth, and regular lung function monitoring are recommended. Exercise-induced asthma patients should use prophylactic medication before exercise and choose low-intensity activities.

  • Environmental Control: Use dehumidifiers to maintain indoor humidity below 50%, and allergen-proof bedding to reduce dust mite exposure
  • Dietary Adjustments: Omega-3 fatty acids may reduce inflammation; vitamin D supplementation can improve lung function in deficient individuals
  • Exercise Management: Regular aerobic exercise can strengthen respiratory muscles, but outdoor activities should be avoided during high pollution periods

Psychological Support

Anxiety and stress can trigger asthma attacks. Cognitive-behavioral therapy and breathing exercises can help patients manage emotions. Building a family support system can improve treatment adherence and self-monitoring capabilities.

Future Directions in Treatment

Genetic research has identified specific gene polymorphisms in airway epithelial cells associated with asthma severity, paving the way for personalized gene therapies. Monoclonal antibody drugs (such as anti-IL-5 therapies) have shown promising results, with ongoing studies to confirm long-term safety.

Digital health applications are emerging, with wearable devices capable of real-time monitoring of respiratory rate and blood oxygen levels, combined with AI to predict exacerbations. Minimally invasive treatments like airway stent implantation are still in clinical trials but offer new hope for refractory asthma.

When to Consult a Specialist

Immediate medical consultation is necessary if: symptoms increase in frequency, nocturnal symptoms interfere with sleep, current medications do not relieve symptoms, or Peak Expiratory Flow (PEF) drops below 80% of personal baseline. Pregnant women and children should have treatment plans re-evaluated by a specialist.

  • Using rescue medication more than twice a month
  • Persistent wheezing after exercise or cold air exposure
  • Continuous decline in lung function tests

Patients should have regular follow-ups every 3-6 months, with lung function tests and symptom diaries to adjust medications. Severe exacerbation signs such as cyanosis, inability to speak, or intercostal retractions require immediate emergency treatment.

 

Frequently Asked Questions

Does long-term use of inhalers cause harm to the body?

Proper use of inhalers is generally safe and effective. However, long-term use of high-dose inhaled corticosteroids may lead to oral thrush or hoarseness. Regular check-ups and following medical advice are essential. Patients should rinse their mouth after inhalation to reduce side effects and attend regular follow-ups for monitoring.

Why do symptoms sometimes not improve immediately after using an inhaler during an attack?

If symptoms do not improve during an acute attack, it may be due to severe airway obstruction or insufficient medication dose. Immediate use of rescue short-acting bronchodilators is recommended. If no improvement occurs within 15-20 minutes, seek urgent medical attention. Patients with poor long-term control should re-assess their treatment plan with their doctor.

What is the evidence for environmental allergen control in asthma management?

Studies show that controlling indoor humidity with dehumidifiers, using dust mite-proof covers, and regular cleaning can reduce exposure to triggers like dust mites by up to 50%. Allergen immunotherapy can also improve airway sensitivity long-term. Discuss personalized strategies with your healthcare provider.

What precautions should asthma patients take when receiving the flu vaccine during flu season?

The flu vaccine can reduce respiratory infections that trigger asthma exacerbations. It should be administered when the condition is stable, with a 30-minute observation period afterward to monitor for allergic reactions. If experiencing an acute asthma attack, control symptoms before vaccination.

Can Traditional Chinese Medicine (TCM) replace Western medication for asthma?

TCM approaches like acupuncture or herbal remedies can serve as adjuncts to treatment, helping to modulate constitution and reduce Western medication doses. However, they cannot independently control moderate to severe asthma. A combined approach under professional supervision is recommended to avoid risks associated with self-medication or abrupt discontinuation.

Asthma