Psoriasis

Psoriasis is a common skin condition
that causes skin redness and irritation.
Most persons with psoriasis have thick,
red skin with flaky, silver-white patches
called scales.


AMGEN'S CANDIDATE IS PROMISING
IN PHASE 2
In April 2012 the New England Journal
of Medicine  published positive phase II
data on Amgen’s  psoriasis candidate,
brodalumab (formerly known as AMG
827).

Results from the 12-week randomized,
double-blind, placebo-controlled, dose-
ranging phase II study, conducted with
198 patients suffering from moderate-
to-severe plaque psoriasis, showed
that brodalumab achieved its primary
endpoint. The mean percentage
improvement in psoriasis area and
severity index (:PASI) was higher in all
brodalumab arms compared to
placebo.

Other companies like Eli Lilly  and
Idera Pharmaceuticals  are also
working on developing treatments for
psoriasis. In fact, phase II data on Eli
Lilly’s candidate was also published in
the New England Journal of Medicine
recently.

Amgen already has a presence in the
psoriasis market in the form of Enbrel.





DEAD SEA SALT
The Dead Sea is a popular center for
wellness and health  due to the fact
that Dead Sea salts have been
reported to have the following benefits:

Rheumatologic Conditions – Dead Sea
salts can be effective in balneotherapy
of Rheumatoid Arthritis, Psoriatic
Arthritis, and Osteoarthritis. The
minerals are absorbed while soaking,
stimulating blood circulation.

Common Skin Ailments – Research
has demonstrated that skin disorders
such as acne and psoriasis are
relieved by regular soaking in water
with added Dead Sea salt.

The National Psoriasis Foundation
recommends Dead Sea and Dead Sea
salts as effective treatments for
psoriasis. One study  concluded that
the high concentration of magnesium
in Dead Sea salt was instrumental in
improving skin hydration and reducing
inflammation.